About Us
ChiroSolve, Inc. is a multi-faceted company providing solutions in various aspects of organic and chiral chemistry research.
Established in September 2005, the company is located near San Francisco, California in close proximity to a number of internationally recognized research universities including Stanford University, U.C. Berkeley, and U.C. San Francisco.
Key Personnel
Dr. Niteen A. Vaidya
Founder and Chief Technology OfficerDr. Niteen A. Vaidya received his Ph.D. in Organic Chemistry from the University of Georgia in 1978. He has over 25 years of experience in chemical research and is recognized as an industry expert in chiral and medicinal chemistry. He has held many technical and executive positions and helped several companies set up their laboratories, initiating research work and implementing successful technology transfers. From 1994 until 2004, he founded and served as CEO of privately held Ychem International. In addition to ChiroSolv® Kits, Dr. Vaidya was responsible (partially or fully) for developing technologies used in a number of other commercial products such as “Sinus Rinse” by Neilmed Pharmaceuticals Inc. and “Flawless” by Advanced Packaging Inc.
Ms. Neelam Vaidya
Co-Founder and Chief Executive OfficerNeelam Vaidya is the co-founder and CEO of ChiroSolve Inc. She holds an MS in Computer Science from Syracuse University and has over 20 years of industry experience in technical, management and business development, mostly in the software industry. Before starting ChiroSolve, Neelam worked for a number of fortune 500 companies like IBM and Sun MicroSystems as well as startup companies. In the past, she was the CEO and Chief Technologist of Perfect Solutions, a software company that developed a number of commercial software products and sold through distributors.
Founders Niteen and Neelam Vaidya created ChiroSolve, Inc. as a means to provide the fine and specialty chemical sectors with improved technology for developing routes to enantiomerically pure compounds. The growing demand for single isomer drugs, agrochemicals, flavor and fragrance ingredients, monomers for chiral polymers and many other compounds has led to the need for more efficient and productive methods for the synthesis of these optically active molecules.
Despite advances in chiral-, chemo- and bio-catalysis technologies, classic resolution via diasteromeric crystallization remains the leading commercial method for obtaining high isomeric purities of chiral compounds. This method, however, has its own limitations. Perhaps most significant is the lack of a means for predicting the appropriate resolving agent and solvent combination that will lead to the best possible yield of product with the highest optical purity.
ChirSolve, Inc. has developed a new high throughput evaluation tool that helps overcome the “trial and error” nature of the technology, resulting in dramatically reduced process development times and measurable cost savings. Chirosolv® kits contain pre-measured quantities of unique combinations of a resolving agent and solvent and can be used to separate enantiomeric mixtures of acids, bases, alcohols, amino acids, aldehydes and ketones. Today, ChiroSolv® kits are being used by such major pharmaceutical companies as Merck, Biogen Idec, Sanofi Group, Pfizer, Johnson & Johnson and are sold worldwide through our distributor Sigma Aldrich.
Besides ChiroSolv® kits, the company offers a range of other chiral resolution services: custom kits as well as Chiral Enhancement Services. Companies with certain research or manufacturing needs can request custom kits tailored to fit their individual needs. Chiral Enhancement Services are also offered to help define a company’s optimal chiral separation process during very early stages of drug development.
