Custom Synthesis
ChiroSolve offers “one stop shop” experience towards outsourced lead discovery and optimization efforts. We can deliver the compounds from milligrams to 50 gm quantity in-house; and can work with our partners to scale-up beyond this quantity. We can deliver:
Organic synthesis: chiral, sugars. Amino acids, peptides, analogs, metabolites, building blocks
API synthesis: fluorescent probes, medicinal chemistry scaffolds, structure-activity relationship
Reference Compounds
Intermediates And Derivatives Of Lead Compounds
Isotopically Labeled And Unlabeled Compounds
Note: All our services are considered “research projects” and we cannot guarantee that the enantiomeric purity will be achieved. Work is done under best-effort basis.
Lead optimization and structure-activity relationship profiling
Rapid derivatisation of small molecules
Synthetic feasibility study
Small-Scale Synthesis of API and Intermediates
Method development and optimization
Custom synthesis of chiral and non-chiral building blocks
Parallel synthesis of focused libraries (lead generation)
Synthesis of metabolites and impurities